2015年Chang首次报道对映选择性C−H官能化研究

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问题：

翻译 The first enantioselective C−H functionalization via the combination of an achiral CpMIII catalyst and a CCA was reported by Chang in 2015. During their studies on the C−H amidation of phosphine oxides 1 with tosyl azide (2) using a CpIrIII catalyst in the presence of carboxylic acid additives, the authors discovered that the pivaloyl protected tartaric acid derivative 3 induces enantioselectivity, although that the selectivity is not sufficient。

回答：

2015年，Chang首次报道了通过结合非手性CpMIII催化剂和CCA实现的对映选择性C−H官能化。在他们研究使用CpIrIII催化剂和羧酸添加剂进行膦氧化物1与对甲苯磺酰叠氮（2）进行C−H氨基化的过程中，作者发现了受保护的叔丁酰基酒石酸衍生物3能够诱导对映选择性，尽管选择性尚不足